Endo S

Endo S is a highly specific endoglycosidase that cleaves within the chitobiose core of N-linked glycans on the Fc region of IgG antibodies. Unlike PNGase F, Endo S is selective for complex-type glycans on immunoglobulins, making it an indispensable tool in glycoprotein characterization, therapeutic antibody research, and quality control testing.

• Enzyme class : EC 3.2.1.96 (Endo-β-N-acetylglucosaminidase S).
• Substrate specificity : IgG Fc glycans (complex-type).
• Molecular weight : ~50 kDa.
• Formulation : Recombinant, high purity.
• Storage : −20 °C; avoid repeated freeze–thaw cycles.