CASP2 antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 2B10
Isotype: IgG1
Immunogen: Caspase 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 18, 32, 50 kDa
Uniprot: P42575
Gene id: 835
Background: CASP2(Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution(PMID:15865942).This antibody can recognize the 32 kDa pro-caspase 2 as well as 18 kDa cleaved-caspase 2.
Field of research: Neuroscience, Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:1000-1:6000
Target: CASP2
Purification: Protein A+G purification
Reactivity: Human
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Clonality: Monoclonal
Clone: 2B10
Isotype: IgG1
Immunogen: Caspase 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 18, 32, 50 kDa
Uniprot: P42575
Gene id: 835
Background: CASP2(Caspase-2) is also named as ICH1, NEDD2 and belongs to the peptidase C14A family.It is involved in the activation cascade of caspases responsible for apoptosis execution and might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.It has 2 isoforms produced by alternative splicing and can exists almost as a dimer in solution(PMID:15865942).This antibody can recognize the 32 kDa pro-caspase 2 as well as 18 kDa cleaved-caspase 2.
Field of research: Neuroscience, Immunology, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:1000-1:6000
Target: CASP2
Purification: Protein A+G purification
Reactivity: Human