EDEM2 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: ER degradation enhancer, mannosidase alpha-like 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 60-65 kDa
Uniprot: Q9BV94
Gene id: 55741
Background: Initiates the endoplasmic reticulum-associated degradation(ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2(PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: EDEM2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: ER degradation enhancer, mannosidase alpha-like 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 60-65 kDa
Uniprot: Q9BV94
Gene id: 55741
Background: Initiates the endoplasmic reticulum-associated degradation(ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2(PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: EDEM2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat